March 1, 2020

Round 9 (Seizure)

Round 9 (Seizure)
Round 9 (Seizure)
EM Clerkship
Round 9 (Seizure)

CAUTION: THESE NOTES CONTAIN SPOILERS!!!



Case Introduction



The nurse brings back a young adult male from the lobby who is having a seizure…



Initial Vitals



* Temp 98.8* HR 90* RR 10* BP 120/80* O2 92%



Critical Actions



* Verbalize ABCs on a Critical Patient* Obtain Immediate Blood Glucose Level* Give Benzodiazepine* Initiate Workup of New-Onset Seizures* Give Pyridoxine (Vitamin B6)



Final Diagnosis



Isoniazid Toxicity



Tips and Tricks



When the patient is unable to provide history, attempt to obtain the information from external sources



Additional Reading



* Isoniazid toxicity overview (Life in the Fast Lane)* Basic approach to seizures (EM Clerkship)* Basic approach to status epilepticus (EM Clerkship)* Ketamine for refractory status epilepticus (PubMed)



Corrections



Ketamine not Keppra as potential induction agent for status epilepticus (32:40)