The Principles of Performance

The Principles of Performance

Discussing the art and science of optimal health, fitness and performance

Podcast 178 – Digital Twins, Peptides, and the AI Driven Future of Longevity with Tony Medrano
The Principles of Performance
Podcast 178 – Digital Twins, Peptides, and the AI Driven Future of Longevity with Tony Medrano

Recent Episodes

178
Oct. 20, 2026

Podcast 178 – Digital Twins, Peptides, and the AI Driven Future of Longevity with Tony Medrano

Tony Medrano is the CEO and co-founder of LongevityPlan.AI, a platform that combines wearable data, biomarkers, medical records, and lifestyle activity into a personalized “Digital Twin” — an AI-powered software replica of the human body built to predict, optimize, and personalize health, recovery, and performance in real time. Through its proprietary Digital Twin for Predictive Peptide Performance™ technology, LongevityPlan.AI delivers physician- supervised peptide protocols and personalized lo
177
Oct. 13, 2026

Podcast 177 – Youth Athletic Development Through Play with Jeremy Frisch

Jeremy Frisch is a nationally recognized leader in youth athletic development, physical literacy, and long-term athletic development (LTAD). He currently serves as Director of Athletic Performance at Teamworks Sports Center in Acton, Massachusetts, and is the former owner and director of Achieve Performance Training in Clinton, Massachusetts, which he built into one of the most respected youth training facilities in the country before selling it after years of successfully developing athletes of
176
Oct. 6, 2026

Podcast 176 – Bleeding Edge Technology for Human Performance and Recovery with David Putrino

David Putrino is the Director of Rehabilitation Innovation for theMount Sinai Health System, Director of the Abilities Research Center (ARC), and Professor in the Department of Rehabilitation and Human Performance at the Icahn School of Medicine at Mount Sinai. Trained as a physical therapist in Australia, David went on to earn a PhD in the neurophysiology of motor control before moving to the United States to study computational neuroscience at Harvard Medical School and MIT, and later to devel
175
Sept. 29, 2026

Podcast 175 – Peptides, Longevity, and the Future of Human Optimization with Dr. Neil Paulvin

Dr. Neil Paulvin is a board-certified osteopathic physician practicing in Manhattan, and one of the most recognized names in longevity and regenerative medicine, often referred to as “The Peptide Doc.” He holds board certifications in Family Medicine, Osteopathic Manipulation, Functional and Integrative Medicine, and Anti-Aging and Regenerative Medicine through the American Academy of Anti-Aging Medicine (A4M), and is a member of the International Peptide Society. His practice combines conventio
174
Sept. 23, 2026

Podcast 174 – Empowering the Evolution of Sport and Human Movement with Joel Smith

Joel Smith is the founder of Just Fly Sports. Joel spent 8 years as a strength coach at the University of California – Berkeley, working across swimming, tennis, water polo, and track and field, and has 17 years of experience coaching track and field at the NCAA, club, and private level. He earned his BA in Exercise Science from Cedarville University and his MS from the University of Wisconsin–La Crosse, and was himself a NAIA All-American track and field athlete. A s a track coach, Joel has gu
173
Sept. 15, 2026

Podcast 173 – Rediscovering Movement and Exercise Through Play with Darryl Edwards

Darryl Edwards is a London-based movement coach, author, speaker, and founder of the Primal Play Method®, an evidence-informed approach to physical activity that draws on exercise physiology, cognitive neuroscience, evolutionary biology, and play psychology to make movement enjoyable, adaptable, and easier to sustain across the lifespan. Darryl holds credentials including FCIMSPA (Chartered Fellow with the Chartered Institute for the Management of Sport and Physical Activity), FBSLM, DFSEM(UK),