Kristen Wiig plays bipolar Alice Klieg, who has opted to eschew her medication and try to make a go of it, much to her therapist's consternation. This leaves her a virtual shut-in, living vicariously through her VHS tapes, many of them of old Oprah Winfrey shows, infomercials, and self-help professors. That is until she hits the California state lottery to the tune of $86 million, then decides to pay an infomercial company to produce a television show called, "Welcome to Me", whereby she can discuss whatever she wants (usually to celebrate herself) on a TV show to be played on daytime TV stations.
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