Sarah Silverman stars as a suburban New Jersey housewife and mother of two, Laney Brooks, whose dedication to her family grows increasingly compromised when she goes off of her medication to treat her depression, then proceeds to drink and take other hard drugs to self-medicate destructively, and even engages in an affair with the husband of one of her friends. Rehab is imminent in order to make things work, but the balance in her mind is not easily achieve, even with her Lithium, as husband Bruce wants to get his wife back to continue to build a life together, but doubts of her own self worth come back to haunt her time and again.
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