Fey and Poehler are uniting seven years after their first big-screen starring pairing in Baby Mama, playing middle-aged siblings, irresponsible and recently unemployed beautician Kate and conscientious-to-a-fault recently divorced nurse Maura, who are shocked when they hear that their parents are selling the Orlando, Florida home the sisters grew up in and need to come out to clear out the bedrooms that have remained largely untouched since they left home in the early 1990s. Their reminiscences while heading back to their old home and sifting through the knick-knacks brings up lots of nostalgia for their youth, to the point where they decide they're going to invite all of their old friends back to "party like its 1989" at the house one last time before it's sold off.