Core IM | Internal Medicine Podcast
Core Internal Medicine via following series:
5 Pearls || Clinically relevant pearls
Mind the Gap || Why do we do what we do?
Gray Matters || Management Reasoning
Hoofbeats || Dissecting clinical reasoning
At the Bedside || Explore everyday challenges
Recent Episodes
223
Nov. 11, 2026
#223 Amyloidosis Presentation: Gray Matters Segment
“Could amyloidosis be the reason behind a patient’s unexplained symptoms?” This episode explores the clinical clues that should prompt clinicians to consider AL amyloidosis and recognize patterns of organ involvement that may otherwise be easy to overlook. Learn how to connect the findings, spot important red flags, and bring amyloidosis into your differential diagnosis. 🔹Sponsor: ACP MKSAP Oakstone CME Use the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP8 🔹Transcript and Sh
222
Oct. 28, 2026
#222 AFib Stroke Prevention: WATCHMAN, DOACs, and the CHAMPION-AF Trial | Beyond Journal Club Segment with NEJM Group
If your patient asks you about a left atrial appendage closure device, what should you tell them? In the latest episode of the Beyond Journal Club podcast from CORE IM and NEJM Group, the hosts will help you: Understand the trade-offs: stroke prevention, bleeding, procedural risks, and medications afterward. Build clinical judgment: weigh which approach may better serve the individual patient, beyond the trial’s headline. Learn from thoughtful counseling: hear how you might discuss the evide
221
Oct. 21, 2026
#221 Colon Cancer Screening After Age 75 | 5 Pearls Segment Part 3
“Should you stop screening for colorectal cancer (CRC) at 75?” This episode explores how to individualize screening decisions based on life expectancy, prior colonoscopy findings, and procedural risks. Learn how to navigate these nuanced conversations, avoid age-based assumptions, and use strategies like mailed FIT kits and offering screening choices to help more patients get screened. 🔹Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery" in your EHR to get home delivery (often same-day).
220
Oct. 8, 2026
#220 Colon Cancer Screening Nuances: 5 Pearls Segment Part 2
“What’s the best way to screen?” This episode breaks down the pros, limitations, and follow-up needs of FIT, Cologuard, CT colonography, and colonoscopy to help you choose the right CRC screening option for your patients. Also learn practical colonoscopy surveillance intervals based on polyp size, number, and pathology. 🔹Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery" in your EHR to get home delivery (often same-day). Learn more here! 🔹Transcript and Show Notes 01:24 | Screening Opt
219
Sept. 29, 2026
#219 Updates in Triglycerides
“The triglycerides are high. Now what?” This episode breaks down a practical approach to elevated TGs, from knowing when to check ApoB or non-HDL-C to choosing lifestyle changes, lipid-lowering medications, and when to suspect an underlying genetic disorder. 🔹Transcript and Show Notes 02:17 | Check a non-HDL-C or ApoB if TGs are ≥150 mg/dL 07:18 | Address waist circumference and lifestyle before meds for high TGs 10:52 | Dr. Watson’s 3-day carbohydrate responsiveness trial 17:07 | Order a fa
218
Sept. 23, 2026
#218 Early-Onset Colon Cancer: 5 Pearls Segment Part 1
“Too young for colon cancer.” This episode unpacks the red flags of early-onset colorectal cancer (CRC), from blood in the stool and iron deficiency anemia to persistent abdominal pain and changes in bowel habits, and offers practical pearls for closing the clinical loop. Also learn why a “negative” family history may need a yearly refresh. 🔹Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery" in your EHR to get home delivery (often same-day). Learn more here! 🔹Transcript and Show Notes