Episodes
30
June 7, 2022
Ep. 30: “Comparative Immunology and Sharks” Featuring Dr. Hanover Matz
Guest: Dr. Hanover Matz is a Postdoctoral Fellow at the University of Maryland, who recently completed his PhD under the supervision of Dr. Helen Dooley. He discusses why sharks may have evolved adaptive immune systems, the role of T cells, mucosal immunity, and antibodies, and working with sharks in the lab. Featured Products and Resources: Keep current with the latest in immune regulation news. Use Easy250 EasySep magnet for rapid immune cell isolation from large-volume samples. The Immuno...
29
May 24, 2022
Ep. 29: “Immuno-Oncology Therapeutics” Featuring Dr. Michael Alonso
Guest: Dr. Michael Alonso is a Scientific Co-Founder, and Vice President of Immunology & Pharmacology at Bolt Biotherapeutics, a biotechnology company developing immunotherapies that activate myeloid cells. He discusses targeting tumors by covering them in “eat me” signals, considerations for moving drugs into the clinic, and building teams in biotech. Featured Products and Resources: Read interviews with immunologists who tell their stories, discuss their research, and voice their opinions o...
May 10, 2022
“AAI 2022: Treg Modulation” Featuring Dr. Alice Long
Guest: Dr. Alice Long is an Associate Member of the Center for Translational Immunology at Benaroya Research Institute at Virginia Mason. The Long lab is focused on understanding how tolerance is lost in autoimmunity, specifically as it related to type 1 diabetes. Dr. Long discusses the work she presented at the American Association of Immunologists’ annual meeting, IMMUNOLOGY2022, on CD8 T cell exhaustion and Treg modulation. Featured Products and Resources: Use EasySep to isolate highly pur...
May 8, 2022
“AAI 2022: Epithelial Immunity” Featuring Dr. Shruti Naik
Guest: Dr. Shruti Naik is an Assistant Professor of Biological Sciences at New York University Langone Medical Center. She studies immunity in the epithelial tissues that line our body to understand how environmental stimuli collaborate with genetic factors to influence health and drive disease at these interfaces. She discusses the work she’s presenting at the American Association of Immunologists’ annual meeting, IMMUNOLOGY2022, on trained immunity and immune-epithelial crosstalk in tissue re...
May 6, 2022
“AAI 2022: Peritoneal Macrophages” Featuring Dr. Gwendalyn Randolph
Guest: Dr. Gwendalyn Randolph is the Emil R. Unanue Distinguished Professor in the Department of Immunology and Pathology at Washington University in St. Louis. Research in her lab integrates the study of monocytes, monocyte-derived cells, and dendritic cells with vascular and lymphatic vessel biology. She discusses the work she’s presenting at the American Association of Immunologists’ annual meeting, IMMUNOLOGY2022, on the diversity, function, and mysteries of peritoneal macrophages. Featured...
28
April 26, 2022
Ep. 28: “Exploring Regulatory T Cells” Featuring Dr. Michael Rosenblum
Guest: Dr. Michael Rosenblum is a Professor of Dermatology at the University of California, San Francisco. His lab seeks to to understand how immune responses are regulated in tissues and how this knowledge can be exploited for therapeutic benefit. They are currently investigating how regulatory T cells (Tregs) control immune responses in tissues, as well as their “alternative” functions. He talks about early-life inflammation and type 2 helper T cells in the skin, and how Tregs can be manipula...
27
April 12, 2022
Ep. 27: “AAI 2022: Building on the Past to Meet the Moment” Featuring Dr. Gary Koretzky
Guest: Dr. Gary Koretzky is President of the American Association of Immunologists, Vice Provost for Academic Integration at Cornell University, Professor of Medicine at Weill Cornell Medicine, and Director of the Cornell Center for Immunology. He talks about how he began his career in immunology, using science to guide Cornell’s response to COVID-19, and what to expect at AAI’s Immunology 2022 meeting taking place May 6-10th. Featured Products and Resources: Use Easy250 EasySep Magnet for ra...
26
March 29, 2022
Ep. 26: “Viruses and Glycoproteins” Featuring Dr. Florian Krammer
Guest: Dr. Florian Krammer is a Professor of Vaccinology at Icahn School of Medicine at Mount Sinai. His lab focuses on understanding broadly-reactive immune responses against the surface glycoproteins of RNA viruses such as influenza, with the goal to develop better vaccines and novel therapeutics. He talks about his lab’s shift to COVID-19 research, strategies for vaccine development, and how we can prepare for future pandemics. Featured Products and Resources: Keep current with the latest i...
25
March 15, 2022
Ep. 25: “Immunology and Industry” Featuring Drs. Andy Kokaji and Hannah Lee
Guest: Dr. Andy Kokaji is a Senior Director of Immunology, and Dr. Hannah Lee is a Senior Director of Product Management, at STEMCELL Technologies. They discuss their career paths and how they develop and commercialize products to support scientists worldwide. Featured Products and Resources: Keep current with the latest in human immunology news. STEMCELL is hiring! The Immunology Science Round Up mRNA Boosters Increase Antibodies but Not Side Effects – A Moderna booster vaccine elicited ne...
24
March 1, 2022
Ep. 24: “Autoimmune Disease” Featuring Dr. Jennifer Gommerman
Guest: Dr. Jennifer Gommerman is a Professor of Immunology at the University of Toronto. Her team has uncovered a novel gut-brain axis that regulates neuroinflammation and is examining the role of B lymphocytes in Multiple Sclerosis (MS) patients and in animal models of MS. More recently, she has been studying the antibody response to SARS-CoV-2 in saliva samples from patients with COVID-19. Featured Products and Resources: Keep current with the latest immune regulation research. Explore scien...
23
Feb. 15, 2022
Ep. 23: “Dendritic Cells and the Immune System” Featuring Dr. Caetano Reis e Sousa
Guest: Dr. Caetano Reis e Sousa is the Assistant Research Director and Senior Group Leader at the Francis Crick Institute. His lab studies the molecular pathways that trigger dendritic cells into action. He talks about the mechanisms of dendritic cell cross-presentation, RNA interference, and dendritic cell progenitors in influenza. Featured Products and Resources: Differentiate Human Monocytes into Dendritic Cells with ImmunoCult Dendritic Cell Culture Kit The STEMdiff Monocyte Kit generates...
22
Feb. 1, 2022
Ep. 22: “Maternal Immune Cells” Featuring Dr. Francesco Colucci
Guest: Dr. Francesco Colucci is a Wellcome Investigator and Professor of Immunology at the University of Cambridge. His research focuses on natural killer (NK) and other innate lymphoid cells, as well as immunogenetics. He talks about uterine NK cells and their education, and falling in love with research as a physician. Featured Products and Resources: Explore scientific resources for your immunology research at the STEMCELL Technologies immunology learning center. Use EasySepTM to isolate h...
21
Jan. 18, 2022
Ep. 21: “Trained Immunity” Featuring Dr. Mihai Netea
Guest: Dr. Mihai Netea is a Professor of Experimental Medicine at Radboud University Nijmegen and a Professor of Immunometabolism at the University of Bonn. He discusses the mechanisms of trained immunity, transmission of immune traits across generations via epigenetics, and how some vaccines can enhance immunity to other pathogens. Featured Products and Resources: Keep current with the latest in human immunology news. Use EasySepTM to isolate highly purified immune cells in as little as 8 min...
20
Dec. 21, 2021
Ep. 20: “Mucosal Immunology” Featuring Dr. De’Broski Herbert
Guest: Dr. De’Broski Herbert is an Associate Professor of Immunology at the University of Pennsylvania. The Herbert lab is exploring the immunoregulatory and regenerative mechanisms operating at the mucosal interface. He discusses his recent paper on IL-33 sources and secretion, his postdoctoral fellowship in South Africa, and the M1/M2 macrophage paradigm. Featured Products and Resources: Keep current with the latest in immune regulation. Use EasySepTM to isolate highly purified immune cells...
19
Dec. 7, 2021
Ep. 19: “Parasitic Infections” Featuring Dr. Keke Fairfax
Guest: Dr. Keke Fairfax is an Associate Professor of Microbiology and Immunology and the Director of Equity, Diversity, and Inclusion at the University of Utah. Her lab uses helminth parasite Schistosoma mansoni as a tool to understand the consequences of IL-4 induced immuno-modulation. She explains how helminth infections can reduce the efficacy of childhood vaccinations, and how mentorship and networking can help minority scientists thrive in Utah. Featured Products and Resources: Keep curre...
18
Nov. 23, 2021
Ep. 18: “Immune Microscopy” Featuring Dr. Tri Phan
Guest: Dr. Tri Phan is a Senior Research Fellow at the Garvan Institute of Medical Research and a Conjoint Professor at the University of New South Wales. He runs the Intravital Microscopy Lab, which aims to understand the checks and balances that control B cell responses. His team uses two-photon microscopy to image cells in live animals, including time-lapses of over 24 hours. He talks about the physics behind this type of microscopy and how it can image deep within tissues without destroying...
17
Nov. 9, 2021
Ep. 17: “Innate Immune Receptors” Featuring Dr. Jenny Ting
Guest: Dr. Jenny Ting is the William R. Kenan Jr. Distinguished Professor of Genetics at the University of North Carolina at Chapel Hill, and served as the President of the American Association of Immunologists from 2020-2021. Her lab discovered the NLR protein family, and their recent research interests include oxidative phosphorylation in HIV, the role of AIM2 in autoimmunity, and microbes that can protect from radiation. Featured Products and Resources: Keep current with the latest in immu...
16
Oct. 26, 2021
Ep. 16: “T Cell Regulation” Featuring Dr. Dario Vignali
Guest: Dr. Dario Vignali is the Frank Dixon Chair in Cancer Immunology and Vice Chair and Professor of Immunology at University of Pittsburgh School of Medicine. His lab studies various aspects of T cell regulation, and recently generated a new mouse model to target conventional CD4 T cells. Featured Products and Resources: Keep current with the latest in immune regulation research. Use EasySepTM to isolate highly purified immune cells in as little as 8 minutes. The Immunology Science Round ...
15
Oct. 12, 2021
Ep. 15: “Tuning the Immune Response” Featuring Dr. Anil Bhushan
Guest: Dr. Anil Bhushan is a Professor at the University of California, San Francisco School of Medicine and Co-Founder of Deciduous Therapeutics, an aging therapeutics company developing a novel class of immune-modulatory therapies. His lab focuses on understanding how the immune system senses and tunes its response to senescent cells in disease and aging, and was one of the first to show the role of clearing senescent cells in models of type 1 diabetes. Featured Products and Resources: Stay ...
14
Sept. 28, 2021
Ep. 14: “Neuroimmunology and Behavior” Featuring Dr. Michael Burton
Guest: Dr. Michael Burton is an Assistant Professor at the University of Texas in Dallas. His lab studies the complex interactions between the immune and nervous systems that lead to pain, depression, and sickness. Featured Products and Resources: STEMCELL Technologies is hiring! Use EasySepTM to isolate highly purified immune cells in as little as 8 minutes. The Immunology Science Round Up Nanoparticle Vaccines for SARS-CoV-2 Variants – Researchers showed that a receptor-binding domain nan...
13
Sept. 14, 2021
Ep. 13: “Pathogens, Autoantigens, and Antigens” Featuring Dr. Frances Lund
Guest: Dr. Frances Lund is the Charles H. McCauley Professor and Chair of the Department of Microbiology at the University of Alabama at Birmingham. Her lab showed that B cells not only make antibodies, but also produce cytokines that modulate the microenvironment. She currently studies the many roles of B cells, how to target B cells gone bad, and nasal vaccines for respiratory illnesses. Featured Products and Resources: Keep current with the latest in infectious disease research. Explore sc...
12
Aug. 31, 2021
Ep. 12: “The Power of Cell Therapy” Featuring Dr. Jeffrey Bluestone
Guest: Dr. Jeffrey Bluestone is the CEO and President of Sonoma Biotherapeutics, a San Francisco and Seattle-based company leveraging the properties of regulatory T cells to create living cell therapies that restore the immune system back to its balanced, fully functioning state. He discusses the company’s research and mission to create therapies that are long-lasting, highly efficacious, and have the potential to slow or prevent autoimmune disease progression and prolong healthy life. Feature...
11
Aug. 17, 2021
Ep. 11: “Adoptive T Cell Transfer” Featuring Dr. Christopher Klebanoff
Guest: Dr. Christopher Klebanoff is a Principal Investigator and Attending Physician at the Memorial Sloan Kettering Cancer Center. His research focuses on cell-based cancer immunotherapies, T cell receptors, and the therapeutic targeting of shared cancer neoantigens. Using single-cell sequencing, biophysical measurements of T cell receptor affinity, genetic engineering, and structural immunobiology, the Klebanoff lab aims to adapt adoptive T cell transfer for advanced solid tumors. Featured Pr...
10
Aug. 3, 2021
Ep. 10: “Viral Pathogens” Featuring Dr. James Crowe
Guest: Dr. James Crowe is the Director of the Vanderbilt Vaccine Center. Their group uses a very broad array of techniques including molecular and cellular biology, state-of-the-art imaging and flow cytometry, bioinformatics, and bioengineering approaches to attack the scientific problems that are of interest to them: major human pathogens. Featured Products and Resources: Immunology of Infectious Disease News Immunology Learning Center The Immunology Science Round Up COVID-19 Vaccine Effec...