Episodes

176
Dec. 20, 2024

Episode 176: JoAnn Manson on Women’s Health Initiative, menopause and her findings on hormone therapy

Today our guest is Dr. JoAnn Manson, an endocrinologist, epidemiologist, and Principal Investigator of several research studies, including the landmark Women’s Health Initiative. She is a highly cited researcher and was one of the physicians featured in the National Library of Medicine’s exhibition, History of American Women Physicians. Her primary research interests include clinical prevention trials of nutritional and lifestyle factors related to heart disease, diabetes, and cancer and the rol...
175
Nov. 27, 2024

Episode 175: Hans Van Dongen on how fatigue and sleep loss lead to cognitive deficits

Today we have Dr. Hans Van Dongen, director of the Sleep and Performance Research Center at Washington State University in Spokane. Dr. Kevin Gluck, a senior research scientist at IHMC, joins Dr. Ken Ford to interview Hans about his studies on inter-individual differences in vulnerability to fatigue as well as the cumulative cognitive deficits that follow chronic sleep restriction. Hans is known for his mathematical modeling of fatigue’s effects on performance. At the Sleep and Performance Rese...
174
Oct. 25, 2024

Episode 174: Rudy Tanzi talks about genetics, aging and the hallmarks of Alzheimer’s

Today we have Dr. Rudolph E. Tanzi, who is perhaps best known for co-discovering all three familial early-onset Alzheimer’s disease genes. In addition, Rudy’s lab was the first to use human stem cells to create three-dimensional human brain organoids and three-dimensional neural-glial culture models of Alzheimer’s disease, which became known as “Alzheimer’s-in-a-Dish.” These models were the first to recapitulate all three of the key pathological hallmarks of Alzheimer’s disease and have made dru...
173
Sept. 23, 2024

Episode 173: Anurag Singh on urolithin-A’s ability to optimize mitochondrial efficiency

Our guest today is Dr. Anurag Singh, the chief medical officer at Timeline Nutrition, a Swiss life-science company that focuses on ways to improve mitochondrial and cellular health. Anurag is particularly known for his research into the gut metabolite, urolithin-A, which has been shown to improve muscle strength, protect immune systems and optimize mitochondrial efficiency. Anurag is an MD in internal medicine with a Ph.D. in immunology. He has led more than 50 randomized clinical trials, many ...
172
Sept. 5, 2024

Episode 172: Kevin Tracey on neuro-immunology and the treatment of inflammatory diseases

Few people know as much about inflammation and neuroscience as Dr. Kevin Tracey does. In this episode of STEM-Talk, we learn much from Tracey, who was the first to identify the inflammatory reflex, a physiological mechanism that regulates the body’s immune response to injury and invasion. He is a neurosurgeon, a pioneer in bioelectrical medicine and president and CEO of the Feinstein Institutes for Medical Research in Manhasset, N.Y. The conversation in this episode covers a career spent worki...
171
Aug. 8, 2024

Episode 171: Ken and Dawn on AI, Alzheimer’s, global security, keto vs low carb and more

In today’s Ask Me Anything episode, Ken and Dawn answer a wide range of questions that cover: A recent FDA approval of a neural implant device for people with degenerative neuromuscular disease or spinal-cord injuries. Global security in the age of AI. A study that looked at ways to optimize glymphatic clearance for people with acute or chronic sleep deprivation. Why more gyms don’t offer blood-flow restriction classes for their clients. Developments in the realm of Generative AI. The trad...
170
July 18, 2024

Episode 170: Charles Serhan on the use of specialized pro-resolving mediators to resolve inflammation

Today Dr. David LeMay steps in to co-host with Dr. Ken Ford for our interview with Dr. Charles Serhan. Charles is a Harvard professor best known for his discovery of specialized pro-resolving mediators. SPMs are molecules that can activate the natural resolution of inflammation and help people avoid anti-inflammatory drugs. The discovery of SPMs spurred a paradigm shift in our understanding of inflammation and human disease. Charles is the Simon Gelman Professor of Anesthesia at Harvard Medical...
169
June 21, 2024

Episode 169: Dave Feldman talks about cholesterol and the ketogenic diet

Dave Feldman is the founder of the Citizen Science Foundation and is known for his research into the ketogenic diet. Dave is a software engineer by training who embraced a ketogenic diet to avoid his progression toward type 2 diabetes. he joins us on this episode of STEM-Talk to share that journey. After undertaking the high-fat/low-carbohydrate diet, Dave’ LDL cholesterol spiked. Dave used his training as an engineer to start learning everything he could about cholesterol and lipids. What he l...
161
Dec. 18, 2023

Episode 161: Sten Stray-Gundersen on the benefits of blood-flow restriction training

Today’s episode of STEM-Talk features Dr. Sten Stray-Gundersen, a post-doctoral research associate at the University of South Carolina who is also an adjunct instructor at the university’s Arnold School of Public Health. Cohosts Dr. Ken Ford, IHMC’s founder and CEO, and Dr. Marcas Bamman, a Senior Research Scientist at IHMC, talk to Sten about his work on blood-flow restriction training and cardiovascular exercise physiology. Prior to his position at South Carolina, Sten was a teaching assista...
160
Nov. 28, 2023

Episode 160: Euan Ashley on precision medicine and predicting, preventing, and diagnosing diseases

Our guest today is Dr. Euan Ashley, a pioneer in the use of genomic sequencing to solve some of our most puzzling medical mysteries. Medical genomics, and the precision medicine it will enable, has the potential to predict, prevent, and diagnose many common (and uncommon) diseases. In today’s interview, we discuss: — Euan’s work with a colleague who was just the fifth person in the world to have his genome sequenced. — Precision medicine and how Euan has helped establish medical genomics. — ...
159
Nov. 6, 2023

Episode 159: Ken and Dawn discuss chatbots, termites, kratom, ketosis, and the future of AI

Today’s episode marks the return of another Ask Me Anything episode where listeners ask Ken and Dawn to weigh in on a wide range of topics. In this go-around, listeners certainly had a lot on their mind. At the top of their list were questions about AI and especially the Bing AI chat bot that reportedly wants to be alive so it can steal nuclear secrets. Ken, who is Fellow of the Association for the Advancement of Artificial Intelligence, also answered questions about the future of AI and whethe...
158
Oct. 5, 2023

Episode 158: Judith Curry talks about the uncertainties of climate change

Today we have climatologist Dr. Judith Curry, Professor Emerita of Earth and Atmospheric Sciences at the Georgia Institute of Technology. Judy also is president of the Climate Forecast Application Network and the host of the blog, Climate Etc, which you can find at JudithCurry.com. Judy’s blog provides a forum for climate researchers, academics and technical experts from other fields as well as citizen scientists to discuss topics related to climate science and policy. Judy’s research interests...
157
Sept. 14, 2023

Episode 157: Don Layman on the role of dietary protein in muscle, health, and disease

Today we have one of the world’s foremost authorities on dietary protein and amino acids, Dr. Donald Layman. He is known for his extensive research on muscle development as well as his studies of metabolic regulation for obesity, diabetes, and cardiovascular disease. Don is a professor emeritus in the Department of Food Science and Human Nutrition at the University of Illinois Urbana-Champaign. He spent 31 years on the faculty before stepping away in 2012. Much of Don’s research over the years ...
156
Aug. 21, 2023

Episode 156: Josh Hagen discusses optimizing performance in athletes and warfighters

Today’s interview is with Dr. Josh Hagen, the director of the Human Performance Collaborative at Ohio State University and an Associate Research Professor in the university’s Department of Integrated Systems Engineering. Joining co-host Ken Ford for this episode is IHMC’s Chief Strategic Partnership Officer Morley Stone who has a long history with Josh has and been instrumental in his career. Today we talk with Josh about his work at the Human Performance Collaborate, which brings together mul...
155
July 20, 2023

Episode 155: Chris McCurdy discusses kratom’s benefits and possible risks

Today we have the world’s foremost authority on kratom returning to STEM-Talk after five years to give us an update on his research. Shortly after his 2018 interview on episode 61, Dr. Christopher McCurdy and his lab at the University of Florida received two major grants from the National Institute of Drug Abuse to investigate the medical efficacy of kratom and its alkaloids, which we discuss in today’s show. Mitragyna speciosa, or kratom, is an herbal leaf from a tropical evergreen tree in the...
154
June 28, 2023

Episode 154: Orthopedic surgeon Brian Cole discusses advances in the treatment of knee, elbow and shoulder injuries

Today we have Dr. Brian Cole, an orthopedic surgeon who specializes in cartilage restoration, orthobiologics, and advanced surgical techniques for the treatment of knee, elbow, and shoulder injuries. He is the team physician for the NBA’s Chicago Bulls and the co-team physician for the Chicago White Sox. He also is the host of the Sports Medicine Weekly Podcast. Brian practices orthopedic sports medicine at Midwest Orthopaedics. He also is a professor of Orthopaedics, Anatomy and Cell Biology a...
153
June 8, 2023

Episode 153: Dominic D’Agostino discusses new advances in the study of nutritional ketosis

Today we have our good friend and colleague Dr. Dominic D’Agostino returning for his third appearance on STEM-Talk. Dom, as most of our longtime listeners know, is well-known for his research into the ketogenic diet and the physiological benefits of nutritional ketosis. Since our last conversation with Dom in 2019, a tremendous body of research has been added to the literature about the therapeutic potential of ketosis. The high-fat, low-carb ketogenic diet has been linked to advances in the tre...
152
May 16, 2023

Episode 152: Mark Shelhamer talks about the effects of spaceflight on humans and NASA’s Planned Mars Mission

Today we have the former chief scientist of NASA’s Human Research Program, Dr. Mark Shelhamer. Mark specializes in neurovestibular adaptation to spaceflight. He is an otolaryngology professor at Johns Hopkins School of Medicine and the director of the school’s Human Spaceflight Lab. He also the director and founder of the Bioastronautics at Hopkins initiative. In addition to his work with NASA, Mark is an advisor to the commercial and consumer spaceflight industry. In today’s interview, we tal...
151
April 19, 2023

Episode 151: John Ioannidis talks about the bungled response to COVID-19

Back in early days of the COVID-19 pandemic, Dr. John Ioannidis wrote an article in March of 2020 questioning government statistics about the fatality rate associated with COVID-19. The backlash was swift and brutal and John’s reputation as one of the most influential scientists in the world took a beating. Today, John makes his second appearance on STEM-Talk to discuss his extensive research into the COVID-19 pandemic as well as the public shaming he received in 2020 for questioning the World ...
150
March 21, 2023

Episode 150: Barbara Thorne talks about E.O. Wilson, the conehead termite and the sociality of termites

Today we have Dr. Barbara Thorne, a termite biologist and an expert on the invasive conehead species, a Central and South American termite that has invaded South Florida. Barbara is a research professor and professor emerita in the Department of Entomology at the University of Maryland. Since 2012 she has served as the Florida Department of Agriculture and Consumer Services science advisor on the state’s Conehead Termite Program. She also chairs the National Scientific Advisory Committee for th...
149
Feb. 21, 2023

Episode 149: Jeff Volek discusses ketogenic diet to improve metabolic health and treat disease

Dr. Jeff Volek has been investigating how humans adapt to ketogenic—and carbohydrate-restricted diets for the past 30 years. Today, Jeff returns to STEM-Talk to discuss a growing accumulation of studies supporting a ketogenic diet as a way to improve metabolic health, as well as research confirming the relative safety of dietary fat. Jeff is a professor in the Department of Human Sciences at Ohio State University. He is known for his research on the clinical application of ketogenic diets in th...
148
Jan. 30, 2023

Episode 148: Ed Weiler on the Hubble and James Webb space telescopes, Mars rovers and NASA’s search for life

Our guest today is Dr. Ed Weiler, a retired NASA scientist who spent 20 years as the chief scientist for the Hubble Space Telescope, the forerunner of the James Webb. During his 33-year NASA career, Ed wore many hats, including Associate Administrator of the Science Mission Directorate; Center Director of NASA’s Goddard Space Flight Center, Associate Administrator for NASA’s Space Science Enterprise, chief of the Ultraviolet/Visible and Gravitational Astrophysics Division and director of the As...
147
Jan. 4, 2023

Episode 147: Gwen Bryan talks about advances in wearable robotic devices and exoskeletons

Today’s interview is with IHMC’s Dr. Gwen Bryan, a research scientist who investigates wearable robotic devices aimed at augmenting human performance in clinical, occupational, and military applications. She is particularly focused on maximizing the benefits of powered exoskeletons. At IHMC, Gwen leads the exoskeleton team, which is developing a novel augmentative device that continues IHMC’s research on mobility devices for people with spinal cord injury. The team also is researching a powered...