Episodes

This episode examines a 2026 study that evaluated a novel diagnostic approach for Johne’s disease using serum microRNA biomarkers and machine-learning algorithms. The researchers aimed to address one of the greatest challenges in Johne’s disease control: the long delay between infection and the point at which currently available tests can reliably identify infected animals. Instead of detecting the pathogen directly, the study focused on identifying specific microRNA signatures associated with i...

This episode investigates a puzzling case in which 10 of 65 pregnant cows died after being moved to a higher, unflooded pasture ahead of a major storm. The move was intended to protect the herd from rising floodwaters, but shortly after the severe weather event, multiple cows were found dead with no obvious signs of disease. Initial necropsies revealed few significant lesions, making the diagnosis especially challenging and shifting suspicion toward a toxic or metabolic cause rather than an infe...

This episode examines how beef producers can improve parasite control by using dewormers strategically rather than treating all cattle routinely. Drawing from a 2026 literature review authored by researchers at Mississippi State University, the discussion highlights how internal parasites can significantly affect cattle health and productivity, particularly in younger animals. Young calves, stockers, and developing heifers typically benefit the most from deworming because they carry heavier para...

This episode examines whether feeding additional vitamin A to cows before calving can improve the vitamin A status of their calves. Reviewing two dairy research studies, the hosts explore how late-gestation supplementation affects vitamin A levels in colostrum, milk, and newborn calves. In the first study, cows received vitamin A at levels slightly above recommended requirements, but researchers found no increase in colostrum vitamin A content and no meaningful improvement in calf blood vitamin ...

This episode examines a 2026 study that explored whether pre-breeding behavior can predict which bulls will sire the most calves in multi-sire breeding pastures. Researchers fitted bulls with collars containing accelerometers and proximity sensors to objectively measure activity levels and social interactions before the breeding season. The goal was to determine whether behavioral traits such as activity, social connectedness, and interaction patterns were associated with a bull’s eventual sirin...

This episode explores how vitamin A nutrition in late-gestation cows affects both maternal health and the vitamin A status of newborn calves. The discussion builds on previous conversations about calf vitamin A deficiencies, emphasizing that colostrum is the primary source of vitamin A for newborn calves and that deficiencies early in life can persist for weeks or months. The hosts review two research studies examining how vitamin A and its precursors are affected by rumen fermentation. The fir...

This case study examines a situation where a producer attempted to control a heavy fly burden by spraying cattle with a topical insecticide, only to have several cows develop severe toxic signs within hours. Affected animals became recumbent, excessively salivated, developed diarrhea, experienced respiratory distress, and showed muscle tremors and weakness, raising immediate concerns about insecticide toxicity. The investigation focused on two common groups of insecticides used in cattle: organ...

In this episode of Bovine Science, we examine a 2024 Journal of Animal Science study that used hundreds of thousands of cattle records to investigate the genetic and environmental influences on fertility in beef cattle. The study evaluated traits including calving date, calving interval, first-calf interval, early calving, and heifer pregnancy. The discussion highlights that most fertility traits have very low heritability, meaning management decisions such as nutrition, body condition, breedin...

This episode reviews a 2026 study investigating whether a modified-live Mycoplasma bovis vaccine can help protect young calves from one of the most frustrating respiratory disease pathogens in the cattle industry. The researchers conducted a controlled challenge trial in neonatal calves, comparing vaccinated and non-vaccinated groups after exposure to Mycoplasma bovis. The results showed several encouraging outcomes for vaccinated calves. They experienced fewer lung lesions, fewer days with fev...

This episode focuses on some of the most challenging cases veterinarians encounter: cattle with vague signs such as weight loss, poor condition, or an unexplained death where no obvious cause is apparent. Dr. Scott Fritz explains that these situations are often far more difficult than classic acute poisonings because there is rarely a clear syndrome, exposure event, or obvious diagnostic clue. Instead, investigations must begin with a thorough history, careful necropsy, and a detailed evaluation...

This episode examines a 2025 study that investigated whether modified-live or killed viral vaccines influence bull breeding soundness exam (BSE) results. The research addressed a common practical question among producers and veterinarians who are concerned that vaccination before breeding season might negatively affect fertility. Researchers randomly assigned mature bulls to receive either a modified-live or killed vaccine and then evaluated semen quality and breeding soundness multiple times ov...

This episode explores the role of vitamin A in beef cow-calf systems and examines why some calves develop low vitamin A levels and respiratory disease even while grazing alongside cows on green pasture. The discussion highlights that vitamin A nutrition is more complex than simply having access to lush forage, because cattle primarily consume beta-carotene from grass, which must be converted into usable vitamin A by the body. A major takeaway is the importance of colostrum as the primary source...

This episode reviews a 2026 Canadian study that evaluated whether vaccinating beef calves against bovine coronavirus could reduce pre-weaning respiratory disease in a commercial cow-calf herd with a history of respiratory problems. The researchers compared vaccinated and non-vaccinated calves under real-world ranch conditions, making the findings especially relevant for producers facing similar challenges. Results showed that vaccinated calves had lower odds of requiring treatment for respirator...

This case study examines a tragic incident in which 14 open heifers died within hours of being separated from a larger group following pregnancy testing. The heifers had been placed in a familiar holding pasture with a functioning water source and secure fencing, leading managers to initially believe the environment was safe. When all 14 animals were found dead later that day, investigators quickly ruled out infectious disease and focused on acute toxic causes due to the rapid onset and 100% mor...

This case study follows the investigation of a puzzling eye disease outbreak affecting approximately 10% of a group of 1,200 stocker cattle shortly after processing and placement on pasture. The affected animals developed severe eye lesions, including corneal cloudiness, swollen eyelids, redness, and inflammation, but lacked many of the classic ulcers typically associated with pinkeye. Because cases appeared almost simultaneously across numerous pastures separated by up to 90 miles, investigator...

This episode examines a study evaluating different nutritional strategies for developing replacement heifers and their impact on puberty attainment. Researchers compared traditional low-gain and high-gain feeding programs with two “stair-step” nutritional approaches that alternated periods of higher and lower energy intake. The goal was to determine whether strategic feeding could achieve the same reproductive outcomes as intensive feeding while using fewer resources. Results showed that the fi...

This episode examines a study investigating whether the physical size of dry lot pens affects the development of replacement heifers, even when animal density remains the same. Researchers compared heifers housed in a standard-sized dry lot, a larger dry lot with the same space per animal, and a pasture-based control group. While growth performance and weight gain were similar across treatments, important differences emerged in behavior, stress indicators, and reproductive development. Heifers ...

This case study examines a sudden and devastating loss in which five cows and two calves died shortly after being moved to a dry lot following the calving season. The affected group consisted of only six cow-calf pairs that had been separated because they were open or had calved late, making the rapid mortality highly suspicious for a toxic exposure rather than an infectious disease. Necropsies revealed few significant findings, while the only surviving cow showed severe neurological signs, incl...

This episode examines research exploring why some cow-calf producers adopt written grazing management plans while others do not. The study was motivated in part by sustainability goals aimed at improving grazing land management, soil health, water infiltration, and drought resilience through more structured planning. Researchers analyzed survey data from producers across the United States to identify factors associated with both written grazing plans and intensive grazing practices. Results sho...

This discussion examines a research study focused on improving long-term profitability in cow-calf operations through better heifer selection. The study used economic modeling and field data to evaluate three key factors: feed efficiency, longevity, and heterosis (hybrid vigor). Results showed that cows with greater genetic diversity consistently generated higher returns, largely due to improved reproductive performance and overall herd productivity. Longevity also played a critical role, as co...

This episode explores a research study evaluating whether sterile saline can effectively replace phosphate-buffered saline (PBS) for collecting samples used in Tritrichomonas PCR testing. The discussion highlights a non-inferiority trial design, which differs from traditional statistical approaches by testing whether one method is not meaningfully worse than another. Researchers created controlled samples with varying concentrations of organisms and compared detection results using both saline a...

This discussion explores the concept of systems thinking in beef cattle production and how it expands beyond traditional population medicine approaches. Systems thinking focuses on understanding how multiple interconnected factors—such as nutrition, environment, disease exposure, and management practices—interact over time to influence herd health and productivity. Many cattle health and performance issues develop gradually, often involving delayed cause-and-effect relationships that can span mo...

This case study from a bovine science discussion examines a sudden and alarming incident in which 12 cows and 2 calves died within 12 hours of routine pre-weaning processing. Initially, the deaths raised concerns about vaccine reactions, toxic exposure, or handling stress, but the pattern of mortality did not align with typical causes. Adult cows, which only received topical parasite treatment, were more affected than calves that received vaccines, further complicating the diagnosis. A necropsy ...

In this episode of BCI Cattle Chat, the hosts explore what the future may hold for the beef industry, discussing trends in cattle size, production inputs, and market prices. They examine the realities of cow-herd expansion and consider how policy decisions could influence cattle production in the years ahead. The conversation also highlights recent research on liver abscesses in feedlot cattle, including how factors such as diet composition, grain processing methods, and days on feed may affect ...